Urea-Stibamine *Please see footnote on p. 162 in which it is shewn that the name urea-stibamine may not be used by any manufacturer of this substance, except Dr. U. N. Brahmachari. We understand that the Union Drug Company are now placing the same compound on the market under the name "Stiburea."—Editor, I.M.G.
نویسنده
چکیده
To the Editor, The Indian Medical Gazette. Sir,?Of the pentavalent antimony compounds that are in common use in the treatment of kala-azar the preparation known as urea-stibamine is probably the one that has been used most extensively. At the Calcutta School of Tropical Medicine we have tried out a large number of. antimony compounds and have selected a number of these as being of special value. When ureastibamine was first introduced by Dr. U. N. Brahmachari and Mr. Judhistir Das, m.sc., the former very kindly sent me a small sample of this preparation for trial; I only treated a few cases but the results were not very good. The published reports of other workers indiciated that the preparation usually gave very much better results than I had obtained, but as I was unable to get further samples of this preparation I could not make a further trial of its therapeutic value for some time. During the last year however Dr. Brahmachari has very kindly given me a generous sample of his preparation and I have been enabled to treat a further series of cases; another small sample sufficient to treat
منابع مشابه
Urea-Stibol in the Treatment of Kala-Azar
" stibacetin," which was the first aromatic compound of antimony to be used in the treatment of leishmaniasis, many aromatic compounds of antimony have been introduced. Von Heyden also introduced sodium meta-chloro-para-acetylamino stibinate, known as No. 471 or " stibosan," and an amine salt of p-amino-phenyl-stibinic acid known as No. 693 iboth of which proved to be very effective in the trea...
متن کاملOn the Toxicity of Some Organic Antimonial Drugs Used for the Treatment of Kala-Azar
are widespread. Some indication of the value of antimony is the fact that without treatment the death rate from kala-azar is over 90 per cent, whereas with treatment in Indian kalaazar it is reduced to below 10 per cent. Although tartar emetic was found of value in the treatment of kala-azar, its considerable toxic effects made it imperative to obtain other derivatives which should be better to...
متن کاملThe discovery of urea stibamine.
W e have recently celebrated the Centenary of Gaspar Vianna and his great discovery o f the value of tartar emetic in the treatment of leishmaniasis.1 It is timely to mention the important work in Calcutta of D octor U pendranath Brahmachari. The problems of toxicity of trivalent inorganic antimonials are well known and between the years of 1915-1921 Brahmachari carried out many experiments in ...
متن کاملFatal Anaphylactic Shock *Rearranged by Editor.
A boy, aged 21 years, had befen suffering from irregular febrile attacks associated with enlarged spleen and liver and progressive anaemia for about nine months. After failure of oral treatment by drugs, the nature of which is not known to the writer, intravenous injection of urea stibamine (Brahmachari) were commenced by a local practitioner. The injections were given at intervals of three or ...
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عنوان ژورنال:
دوره 61 شماره
صفحات -
تاریخ انتشار 2017